Post-Operative Mortality in CABG Patients With Co-Morbid T2DM

doi:N/A

eISSN: 1994-4624 / ISSN: 1813-176x

International Journal of Molecular Medicine and Advance Sciences

2020, Volume 16, Issue 1 : 6-9

Research Article

Post-Operative Mortality in CABG Patients With Co-Morbid T2DM

Ayesha Rahman

Daniel K. Roberts

Hemant Kumar

Department of Cardiac Surgery, Apollo Heart Institute, Kolkata, India

Division of Cardiothoracic Sciences, New York Heart Center, NY, USA

Department of Cardiovascular Surgery, Global Medical College & Hospital, Mumbai, India

Received

Jan. 9, 2020

Revised

Feb. 23, 2020

Accepted

March 16, 2020

Published

April 30, 2020

Abstract

Coronary artery bypass grafting (CABG) is an essential revascularization intervention for advanced coronary artery disease (CAD). However, co-morbid Type 2 Diabetes Mellitus (T2DM) significantly increases postoperative morbidity and mortality due to endothelial dysfunction, platelet activation, and impaired wound healing. This retrospective multicenter study evaluated 3,200 CABG patients from 2019–2024 across five tertiary cardiovascular centers. Patients were grouped into diabetic (T2DM, n=1,450) and non-diabetic cohorts (n=1,750). Post-operative mortality was assessed at 30-days, 6-months, and 1-year. Results demonstrated significantly higher mortality in the diabetic group (30-day mortality: 6.8% vs 3.1%), driven by sepsis, graft occlusion, and renal failure. Long-term mortality remained elevated, particularly in insulin-dependent patients. Findings stress the importance of glycemic optimization and tailored post-operative care protocols for diabetic patients undergoing CABG.

Keywords

CABG

Type 2 Diabetes Mellitus

Cardiovascular surgery

Post-operative mortality

Graft failure

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