Physiology of Vitamin D

doi:ijmmas.2011.1.4

eISSN: 1994-4624 / ISSN: 1813-176x

International Journal of Molecular Medicine and Advance Sciences

2011, Volume 7, Issue 1 : 1-4 doi: ijmmas.2011.1.4

Research Article

Physiology of Vitamin D

DOI : ijmmas.2011.1.4

Published

Sept. 30, 2005

Abstract

Vitamin D is relevant to several processes in the body mainly in the intracellular mechanisms affecting parathyroid hormone and calcitonin regulation, regulation of vitamin D production by negative feedback and calcium and phosphorous level regulation. Vitamin D may be synthesised in the dermal layer of the skin or absorbed through the diet and utilised. Its biosynthesis initiates from cholesterol and its derivatives and is followed by a cascade of reactions, completed in the kidneys and transported via the blood to where it is utilized. The vitamin D receptor determines the physiological effects of vitamin D and any mutations will cause imbalances in bone homeostasis.

Keywords

Dihydrocholecalciferol

Vitamin D receptor

Calcium

Parathyroid hormone

Phosphate

Calcitonin

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