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International Journal of Molecular Medicine and Advance Sciences
2020, Volume 16, Issue 2 : 24-28
Research Article
Outcomes of ASD Device Closure Under Local vs General Anesthesia: A Comparative Clinical Study
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1
Department of Cardiology, HeartCare Superspeciality Hospital, Bangalore, India
2
Division of Cardiac Intervention, Asian Medical Institute, Kuala Lumpur, Malaysia
3
Center for Epidemiology & Cardiovascular Biostatistics, University of Bristol, UK
Received
Sept. 20, 2020
Revised
Oct. 23, 2020
Accepted
Nov. 16, 2020
Published
Dec. 30, 2020
Abstract

Atrial Septal Defect (ASD) device closure is an established minimally invasive alternative to surgical repair. Traditionally, these procedures are performed under general anesthesia (GA), but local anesthesia (LA) with conscious sedation is increasingly being preferred due to reduced complications, faster recovery, and lower procedural cost. This retrospective multi-center study compares clinical outcomes of ASD device closure performed under LA (n=340) vs GA (n=280) across a 6-year period. Primary outcomes include procedural success, hemodynamic stability, complications, fluoroscopy time, and hospital stay. Results indicate comparable success rates (LA 97.9%, GA 98.6%) but LA significantly reduced hospital stay (1.2 vs 2.7 days), anesthesia-related adverse events (1.8% vs 8.6%), and total cost. This study suggests that LA is a safe and cost-effective alternative for most adult ASD closures, though GA remains preferable in pediatric and anxious patients.

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