Large number of applications is associated with heat transfer in muscle and skin tissues and thermal therapy applications. Blood flow plays an important role in determining the effectiveness of thermal therapy. In general, the effect of blood flow on temperature distribution in tissue is considered as cooling due to both thermally significant large vessels and smaller microvasculature during thermal treatments. Transportation of particles (tissue cells) and interconnected voids that contain either arterial or venous blood through porous media has significant applications of biomedical systems such as biological tissues which include flow, heat and mass transfer through porous media. By applying the porous medium model to describe the heat transfer and effect of shear stress in living tissue, an analytical solution is obtained. It is observed that as the porous parameter is increased, the wall shear stress and heat transfer rate also increases. It has been also investigated that as the heat transfer rate is increased, the wall shear stress also increases.