Phhytochemical studies of five varieties of citrus species; sweet orange (<I>Citrus sinensis)</I>, tangerine (<I>Citrus reticulata)</I>, lemon (<I>Citrus limonum</I>), lime (<I>Citrus aurantifolia)</I> and grape (<I>Citrus grandis)</I> revealed the presence of bioactive compounds comprising alkaloids (0.33-0.04 mg 100 g <SUP>1</SUP>), flavonoids (0.19-0.57 mg 100 g <SUP>1</SUP>), phenols (0.01-0.42 mg 100 g <SUP>1</SUP>) and tannins (0.01-0.04 mg 100 g <SUP>1</SUP>). These citrus fruits are good sources of water-soluble vitamins: ascorbic acids (19.36-61.60 mg 100 g <SUP>1</SUP>), riboflavin (0.01-0.11 mg 100 g <SUP>1</SUP>), thiamin (0.06-0.12 mg 100 g <SUP>1</SUP>) and niacin (0.03-0.43 mg 100 g <SUP>1</SUP>). These phytonutrients and vitamins may be responsible for the antioxidants, anticancer, anti-inflammatory properties of the citrus species. The citrus spices have their popular use in herbal medicine and as fruits in Nigeria.