Effects of Acetylsalicylic Acid on Blood Flow Through an Artery under Atherosclerotic Condition

doi:ijmmas.2011.19.24

eISSN: 1994-4624 / ISSN: 1813-176x

International Journal of Molecular Medicine and Advance Sciences

2011, Volume 7, Issue 4 : 19-24 doi: ijmmas.2011.19.24

Research Article

Effects of Acetylsalicylic Acid on Blood Flow Through an Artery under Atherosclerotic Condition

DOI : ijmmas.2011.19.24

Published

Dec. 30, 2005

Abstract

Acetylsalicylic acid is a salicylate drug which is used to decrease viscosity of blood by diluting the blood which ultimately decreases the blood pressure of the patients. The effects of peripheral layer on blood flow characteristics due to the presence of a mild stenosis are also studied in this study. A two Fluid Model for blood flow through abnormally constricted stenosed artery has been developed. The model consists of a core region of suspension of all erythrocytes assumed to be Bingham Plastic Fluid Model, to find the effects of peripheral-layer viscosity and a peripheral plasma layer free from cells of any kind of Newtonian fluid is considered. It is shown that the magnitudes of the flow characteristics significantly increase with stenosis shape parameter and the peripheral layer causes marked reduction in the magnitudes of the flow characteristics. Physiological relevance and the influence of various parameters are discussed.

Keywords

Peripheral layer

Bingham Plastic Fluid Model

Apparent viscosity

Stenosed artery

Newtonian fluid

Atherosclerosis

Resistance to blood flow

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