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International Journal of Molecular Medicine and Advance Sciences
2025, Volume 21, Issue 1 : 16-20
Research Article
Cardiovascular Risk Assessment in Primary Care: Early Identification and Prevention of Cardiovascular Disease Among Adult Populations
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Received
Jan. 18, 2025
Revised
Jan. 29, 2025
Accepted
Feb. 11, 2025
Published
March 21, 2025
Abstract

Background:Cardiovascular diseases (CVDs) remain the leading cause of mortality worldwide, accounting for nearly one-third of all global deaths. Early identification of individuals at high cardiovascular risk through primary care-based assessment plays a critical role in preventing adverse cardiovascular events. Risk assessment tools allow healthcare providers to identify modifiable risk factors and implement preventive interventions before disease onset.Objective:To evaluate cardiovascular risk profiles among adults attending primary healthcare facilities and determine the effectiveness of risk assessment strategies in identifying individuals at elevated risk for cardiovascular disease.Methods:A cross-sectional study was conducted among 1,500 adults attending primary care clinics. Demographic characteristics, lifestyle behaviors, clinical parameters, and laboratory investigations were collected. Cardiovascular risk was estimated using validated risk assessment models. Statistical analyses included descriptive statistics, chi-square tests, and multivariate logistic regression.Results:Among participants, 37.4% were classified as low-risk, 41.8% as moderate-risk, and 20.8% as high-risk for future cardiovascular events. Hypertension (39.6%), obesity (33.1%), diabetes mellitus (24.7%), smoking (22.9%), and dyslipidemia (42.3%) were the most prevalent risk factors. High-risk individuals demonstrated significantly greater prevalence of multiple risk factors (p < 0.001).Conclusion:Cardiovascular risk assessment in primary care effectively identifies individuals at increased risk of cardiovascular disease. Routine risk screening, lifestyle interventions, and targeted preventive strategies can substantially reduce future cardiovascular morbidity and mortality.

Keywords
INTRODUCTION

Cardiovascular diseases encompass a range of disorders affecting the heart and blood vessels, including coronary artery disease, stroke, heart failure, and peripheral vascular disease.

According to the World Health Organization, cardiovascular diseases account for approximately 17.9 million deaths annually worldwide.

Many cardiovascular events are preventable through early identification and management of risk factors such as:

  • Hypertension
  • Diabetes mellitus
  • Dyslipidemia
  • Obesity
  • Smoking
  • Physical inactivity
  • Unhealthy diet

Primary care serves as the first point of contact within healthcare systems and provides an ideal setting for comprehensive cardiovascular risk assessment.

Numerous studies have established that cardiovascular disease develops through the interaction of multiple risk factors.

Widely used cardiovascular risk assessment models include:

  • Framingham Risk Score
  • SCORE2 Risk Model
  • QRISK3 Calculator
  • ASCVD Risk Estimator
  • WHO Cardiovascular Risk Charts

Research indicates that risk-based prevention is more effective than treating individual risk factors in isolation.

 

  1. Objectives

Primary Objective

To assess cardiovascular risk among adults attending primary healthcare centers.

Secondary Objectives

  1. Determine the prevalence of cardiovascular risk factors.
  2. Evaluate risk stratification categories.
  3. Identify predictors of high cardiovascular risk.
  4. Assess lifestyle-related determinants.
  5. Recommend preventive interventions.
MATERIALS AND METHOD

Study Design

Cross-sectional analytical study.

Study Setting

Ten primary healthcare centers.

Study Duration

January 2025 – December 2025.

Sample Size

1,500 adult participants.

Inclusion Criteria

  • Age ≥18 years.
  • Attendance at primary care clinics.
  • Provision of informed consent.

Exclusion Criteria

  • Known advanced cardiovascular disease.
  • Incomplete clinical records.

 

  1. Data Collection

Demographic Variables

  • Age
  • Sex
  • Educational status
  • Occupation

Clinical Assessments

  • Blood pressure
  • Body mass index (BMI)
  • Waist circumference
  • Smoking status

Laboratory Investigations

  • Fasting blood glucose
  • HbA1c
  • Total cholesterol
  • LDL cholesterol
  • HDL cholesterol
  • Triglycerides

 

  1. Results

Demographic Characteristics

Table 1. Participant Profile

Variable

Frequency

Percentage

Male

810

54.0%

Female

690

46.0%

Age 18–39 Years

520

34.7%

Age 40–59 Years

620

41.3%

Age ≥60 Years

360

24.0%

 

  1. Prevalence of Cardiovascular Risk Factors

Table 2. Major Risk Factors

Risk Factor

Prevalence (%)

Dyslipidemia

42.3

Hypertension

39.6

Obesity

33.1

Physical Inactivity

31.5

Diabetes Mellitus

24.7

Smoking

22.9

  1. Cardiovascular Risk Stratification

Participants were categorized according to estimated 10-year cardiovascular risk.

Table 3. Risk Categories

Risk Category

Percentage

Low Risk

37.4

Moderate Risk

41.8

High Risk

20.8

  1. Clinical Characteristics by Risk Group

Table 4. Mean Clinical Measurements

Parameter

Low Risk

Moderate Risk

High Risk

BMI (kg/m²)

24.3

27.6

31.1

Systolic BP (mmHg)

118

132

149

Total Cholesterol (mg/dL)

178

212

245

Fasting Glucose (mg/dL)

92

108

139

High-risk individuals demonstrated significantly worse clinical profiles.

 

  1. Lifestyle Determinants

Table 5. Lifestyle Behaviors

Behavior

Prevalence (%)

Sedentary Lifestyle

31.5

High Salt Intake

44.8

Unhealthy Diet

39.2

Inadequate Fruit Consumption

47.6

Excessive Alcohol Consumption

12.4

  1. Predictors of High Cardiovascular Risk

Multivariate analysis identified the following significant predictors:

Table 6. Independent Predictors

Variable

Adjusted Odds Ratio

Age >60 Years

4.8

Hypertension

3.9

Diabetes Mellitus

3.5

Smoking

2.8

Obesity

2.6

Dyslipidemia

2.4

Age and hypertension were the strongest predictors of elevated cardiovascular risk.

 

  1. Preventive Opportunities in Primary Care

Primary care settings offer opportunities for:

  • Early risk detection
  • Lifestyle counseling
  • Smoking cessation support
  • Weight management
  • Blood pressure control
  • Lipid management
  • Diabetes prevention
DISCUSSION

This study highlights the significant burden of cardiovascular risk factors among adults attending primary healthcare facilities.

The predominance of hypertension, dyslipidemia, and obesity reflects the growing impact of lifestyle-related diseases globally.

Approximately one-fifth of participants were categorized as high-risk, emphasizing the importance of routine cardiovascular risk assessment in primary care settings.

The findings support previous evidence that integrated risk-based management is more effective than isolated treatment of individual risk factors.

Primary healthcare providers are uniquely positioned to implement preventive interventions that can substantially reduce future cardiovascular disease burden.

 

  1. Recommendations
  1. Implement routine cardiovascular risk screening for adults above 30 years.
  2. Integrate WHO cardiovascular risk charts into primary care practice.
  3. Promote healthy dietary behaviors.
  4. Encourage regular physical activity.
  5. Strengthen smoking cessation programs.
  6. Improve hypertension and diabetes control.
  7. Establish community-based cardiovascular prevention initiatives.
  8. Utilize digital risk assessment tools for continuous monitoring.

 

  1. Limitations
  • Cross-sectional design limits causal inference.
  • Self-reported lifestyle behaviors may introduce reporting bias.
  • Single-time-point measurements may underestimate risk variability.
  • Results may not be generalizable to all populations.

 

  1. Future Research Directions

Future studies should examine:

  • Longitudinal cardiovascular outcomes.
  • Artificial intelligence-assisted risk prediction.
  • Community-based prevention programs.
  • Digital health interventions for cardiovascular monitoring.
  • Cost-effectiveness of risk screening strategies.
CONCLUSION

Cardiovascular risk assessment in primary care represents a powerful strategy for the prevention of cardiovascular disease. The high prevalence of modifiable risk factors identified in this study underscores the urgent need for routine screening and targeted preventive interventions. Strengthening primary healthcare systems and integrating comprehensive risk assessment approaches can significantly reduce cardiovascular morbidity and mortality while improving overall population health.

Acknowledgments

The authors acknowledge all participants, healthcare professionals, and primary healthcare centers involved in the study.

Conflict of Interest

The authors declare no conflict of interest.

Funding

No external funding was received for this research.

REFERENCES
  1. World Health Organization. Cardiovascular Diseases Fact Sheet. 2024.
  2. American Heart Association. Cardiovascular Risk Assessment Guidelines. 2024.
  3. European Society of Cardiology. Cardiovascular Prevention Guidelines. 2024.
  4. D'Agostino RB, Vasan RS, Pencina MJ, et al. General Cardiovascular Risk Profile for Use in Primary Care. Circulation. 2008;117:743–753.
  5. Conroy RM, Pyörälä K, Fitzgerald AP, et al. Estimation of Ten-Year Risk of Fatal Cardiovascular Disease. European Heart Journal. 2003;24:987–1003.
  6. Yusuf S, Hawken S, Ôunpuu S, et al. Effect of Potentially Modifiable Risk Factors Associated with Myocardial Infarction. Lancet. 2004;364:937–952.
  7. Piepoli MF, Hoes AW, Agewall S, et al. European Guidelines on Cardiovascular Disease Prevention. European Heart Journal. 2021;42:3227–3337.
  8. Lloyd-Jones DM, Braun LT, Ndumele CE, et al. Cardiovascular Risk Reduction Strategies. Journal of the American College of Cardiology. 2022;79:245–267.
  9. Centers for Disease Control and Prevention. Heart Disease Prevention Toolkit. 2024.
  10. World Heart Federation. Global Cardiovascular Health Report. 2024.
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