eISSN: 1994-4624 / ISSN: 1813-176x
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International Journal of Molecular Medicine and Advance Sciences
2006, Volume 2, Issue 2 : 231-235 doi: ijmmas.2006.231.235
Research Article
Acceleration of Wound Healing by Aqueous Extract of <I>Allium sativum </I>in Combination with Honey on Cutaneous Wound Healing in Rats
Published
Dec. 30, 2005
Abstract

"The aqueous extract of garlic <I>(Allium sativu</I>m) in combination with honey was evaluated for wound
healing activity in rats. Three groups of male <I>Sprague dawley </I>rats each consist of 6 animals. Rats were
experimentally wounded in the posterior neck area. A thin layer of pure unboiled honey was applied topically
to wounds of Group 1 animals. <I>A. sativum </I>L. in combination with honey was applied topically to wounds of
Group 2 rats and a thin layer of solcoseryl - jelly was applied topically to wounds of Group 3 animals. The
effects of these topical applicants on the rate of wound infections and on the rate of wound healing were
assessed. Wounds of all animals showed clean and remain sterile throughout the experiment until complete
healing. Wounds treated with garlic extract in combination with honey significantly accelerate wound healing
compared to wounds treated with honey alone. In addition, wounds treated with solcoseryl-jelly also
significantly accelerates wound healing compared to wounds treated with honey alone. These results strongly
document the beneficial effects of garlic extract in combination with honey for the acceleration of wound
healing process and the rates of wounds sterility."

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