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International Journal of Molecular Medicine and Advance Sciences
2011, Volume 7, Issue 3 : 16-18 doi: ijmmas.2011.16.18
Research Article
4-Methylphenylsemicarbazone Derivatives Inhibits Cow Milk Induced Pyrexia in Rabbits
Published
March 30, 2005
Abstract

A series of 4-methylphenylsemicarbazone was synthesized and investigated for their antipyretic activity using boiled cow milk induced pyrexia in rabbits. It was observed that the compound 4MS-8 exhibited maximum protection against pyrexia. Hydroxy substitution in aldehydic and acetophenic moiety of 4-methylphenylsemicarbazone derivatives significantly increased antipyretic activity.

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